ABSTRACT
Introduction: Celery (
Apium graveolens L.) is a member of the
Apiaceae family that
can grow everywhere. Celery contains flavonoids, saponins, tannins, essential oils,
apigenin, choline, vitamins A, B, C, asparagine bitter substances. Celery contains
flavonoids, saponins, and tannins which are antibacterial compounds.
Streptococcus
mutans is a Gram-positive bacterium creating an acidic atmosphere in the oral cavity,
which causes insufficient saliva to prevent enamel demineralisation which can lead to
dental caries. The purpose of this study was to analyze the inhibition effect of celery leaf
extract (
Apium graveolens L.) on the growth of
Streptococcus mutans. Methods: This
type of experimental laboratory research uses the Post Test Only Control Group Design.
The samples were
Apium graveolens L. and
Streptococcus mutans ATCC 25175. The
number of treatment groups was 24 with concentrations of 20, 40, 60, and 80%.
Toothpaste containing antibacterial ingredients was used as positive control and for
negative control, a basic toothpaste formula without antibacterial ingredients, namely
carboxymethyl cellulose (CMC), xylitol, calcium carbonate (CaCO3), sorbitol, sodium
lauryl sulphate (SLS), natrium benzoate. Data analysis using one-way ANOVA test with
normality test using Shapiro-Wilk and homogeneity test using Levene test. The results
at a concentration of 20, 40, 60 and 80% with a positive control there was no significant
difference because the sig value was >0.05. Results: The results showed that Celery
containing toothpaste inhibits
Streptococcus mutans growth (p value <0.05) that there
is a significant inhibition effect of
Apium graveolens L. extract toothpaste on the growth
of
Streptococcus mutans. Conclusion: There is an inhibition effect of celery leaf (
Apium
graveolens L.) extract toothpaste on the growth of
Streptococcus mutans.