Nasopharyngeal carcinoma is a malignant tumor on head that located exactly behind nasal to the base of cranium. In 2011, there have increased asopharyngeal carcinoma patients annually with average 17 patients per month at Gatot Subroto Hospital Jakarta. Chemoteraphy drug is the one of drugs that can inhibit cancer growth and kill cancer cells. The purpose of this study is to determine the response of histopathological classifications on nasopharyngeal carcinoma patients after had treatment of chemoradiotherapy within 1 year. This research is a descriptive analytic research that using cross sectional method. The technique of sampling uses purposive sampling, which is to determine the sample of the population that have certain characteristics to fill quota that needed. Total sampels are 42 people from secondary data using medical record of patients, who have treated
chemoradiotherapy for 1 year. The alternative test uses Fisher's test, that the results of significancy value is 0.005. Therefore, we can conclude that there is correlation between chemoradioteraphy response and nasopharyngeal carcinoma patients that based on WHO classifications.